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MSRI Summer Graduate Workshop: Mathematical aspects of computational biology

June 19, 2006 to June 30, 2006
Organized By: Reinhard Laubenbacher (Virginia Bioinformatics Institute at Virginia Tech) and Lior Pachter (Department of Mathematics, UC Berkeley)
 
Participant List:
View a List of Registered Participants
 
This workshop will be specifically focused on the mathematical aspects of computational biology.

Workshop Schedule

Topics
We need a hierarchy of scales to understand and integrate the knowledge gained from the landmark undertaking of mapping the human genome sequence. Understanding of how the vast variety of biochemical compounds, including proteins and metabolites, interact with each other and form complex reaction networks is the next step. These networks comprise the complex cellular interaction networks of cell metabolism. Organism and population scales above these require yet different analysis tools.

In this workshop we will focus on the first two scales: the genome and intracellular biochemical reaction networks, including gene regulatory networks. The course will be organized around the following datasets:
  • The yeast genome(s)

  • The human genome, completed and finished to high quality in 2004

  • Time series of yeast DNA microarray measurements, including a control and response to oxidative stress, generated at VBI

Workshop activities involving these data sets are as follows:
  • Find orthologs and homologs to yeast genes involved in oxidative stress response in the human genome, in order to find candidate genes for an oxidative stress response network in human tissue

  • Create mathematical models of network dynamics for the yeast oxidative stress network, using several modeling methodologies from both continuous and discrete mathematics

The workshop will provide background lectures in Biology and Mathematics.

Priority for this workshop is given to graduate students at MSRI Academic Sponsoring Institutions. If you are at one of these institutions, request your Director of Graduate Studies to nominate you. After these nominations are in, applicants will be considered for admission and possible funding, if such funding is still available. These considerations will take place before April 15, 2006.
 

Follow this link to read about the new U.S. visa requirements

 

Currently Available Videos

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